In Vitro Fertilisation (IVF)

in Greece with High Success Rates

What is In Vitro Fertilisation (IVF)?

In Vitro Fertilization (IVF) is the most widely used and effective method of assisted reproduction. As its name indicates, it is the process in which the fertilization of the egg by the sperm occurs outside the body under laboratory conditions, rather than in the woman’s fallopian tubes as in natural conception.

Despite the use of advanced laboratory techniques, the eggs and sperm belong to the couple themselves, and the embryos created are carefully transferred back into the uterus with the aim of achieving implantation and pregnancy.

IVF is commonly recommended in cases of infertility caused by fallopian tube problems, male factor infertility, ovarian dysfunction, or unexplained infertility. Since the birth of the first IVF baby in 1978, the field of assisted reproduction has advanced significantly, offering hope and effective solutions to millions of couples worldwide.

The Stages of In Vitro Fertilisation (IVF)

The journey to pregnancy, step by step

Step 1

Preparation and Fertility Testing

The first stage of the process involves a detailed medical examination and discussion with the doctor to understand the couple's history and identify any potential obstacles to fertility. Blood tests, transvaginal ultrasound, semen analysis and hormone markers are performed to develop a personalised IVF plan. At the same time, instructions are given on dietary and lifestyle changes that increase the chances of success. A strong body before conception is the first step to a healthy pregnancy.

Tiny newborn feet and hands, symbolizing the joyful outcome of a successful IVF journey.

Step 2

Ovarian Stimulation & Egg Retrieval

Once the preparation phase is completed, ovarian stimulation begins with the daily administration of fertility medications for approximately 9–12 days, in order to stimulate the development of multiple ovarian follicles. During this phase, the patient undergoes frequent ultrasound examinations and blood tests to monitor the response of the ovaries and the growth of the follicles. When the follicles reach the appropriate size, egg retrieval (oocyte retrieval) is scheduled. Egg retrieval is a short procedure lasting only a few minutes, during which the eggs are collected from the ovaries under light sedation. The retrieved eggs are then fertilized in the laboratory using sperm from the partner or a donor.

Doctor and patient discuss IVF using a uterine model during a consultation with ultrasound screen visible.

Step 3

Embryo transfer & waiting

The fertilised eggs are monitored by specialist embryologists as they develop for 3 to 5 days. The best embryo is then selected for transfer to the uterus — a simple and painless procedure that does not require anaesthesia. The remaining healthy embryos can be cryopreserved for future use. After embryo transfer, the waiting period begins, and approximately 10-12 days later, a pregnancy test is performed by testing for beta-hCG in the blood.

Micropipette precisely injects fluid into a petri dish during the critical IVF laboratory procedure.

In Vitro Fertilisation Methods

The choice of the most appropriate IVF method is always made on an individualized basis, taking into account the medical evaluation and the specific needs of each patient. The main IVF approaches include the natural cycle, the modified natural cycle, mild ovarian stimulation, and conventional (full) ovarian stimulation. Each approach has its own characteristics, advantages, and limitations.

In Vitro Fertilisation in the Natural Cycle

In a natural IVF cycle, no ovarian stimulation medications are used, except for a single trigger injection administered shortly before egg retrieval to induce final oocyte maturation. The process follows the natural development of a single follicle, from which one egg is collected and fertilized in the laboratory.

This method is less invasive and lower in cost, but it is associated with lower success rates and a higher risk of not obtaining a viable embryo. It is typically recommended for women with diminished ovarian reserve or for those who prefer a more natural approach to fertility treatment.

Modified Natural Cycle

This approach is based on the natural development of a single follicle, but it is supported by low doses of medication to prevent premature ovulation.

As a result, the simplicity of the natural cycle is maintained while significantly reducing the risk of cycle cancellation. It is considered a safer alternative for women with limited ovarian reserve or for those who prefer minimal medical intervention.

Mild stimulation

In mild ovarian stimulation, lower doses of fertility medications are used for a shorter duration compared to conventional IVF protocols, aiming to produce a small number of high-quality follicles.

This approach offers good success rates while reducing the risk of ovarian hyperstimulation syndrome (OHSS). It represents a balanced option, combining better outcomes than the natural cycle with less medication burden than full stimulation.

Conventional (Full) Ovarian Stimulation IVF

This is the most commonly used IVF approach, in which the patient receives higher doses of gonadotropins in order to stimulate the development of multiple follicles.

It offers the highest success rates per cycle and is often considered the preferred option when the goal is to maximize the number of eggs retrieved. Although it involves higher medication use and increased treatment cost, it may reduce the need for repeated treatment cycles.

Advanced IVF Techniques

For even greater precision and improved outcomes, IVF can be combined with specialized advanced techniques, depending on the needs of each couple.

What does the cost of IVF include?

In vitro fertilization (IVF) is a complex medical process, and its cost is not identical for every patient. Instead, each treatment plan is individually designed based on the couple’s specific needs and medical indications. For this reason, it is important to understand what the overall pricing may include in order to make a well-informed decision.

The total cost may include ovarian stimulation, egg retrieval, fertilization (IVF or ICSI), embryo transfer, blastocyst culture, as well as the use of specialized techniques such as PICSI or EmbryoGlue. Additional options may also be available, including egg freezing or embryo cryopreservation.

Prices may vary depending on the treatment protocol selected, such as a natural cycle, full ovarian stimulation, or egg donation, as well as the specific laboratory techniques required during treatment.

Talk to an Expert

Frequently Asked Questions About IVF

What are the basic stages of IVF?

The process includes: ovarian stimulation with medication, egg retrieval (oocyte retrieval), fertilisation in the laboratory (IVF or ICSI), embryo culture and finally embryo transfer to the uterus. The entire process takes approximately 2–3 weeks.

How many IVF attempts are needed on average to be successful?

The success rate depends on several factors, including the woman’s age, the quality of the eggs and sperm, and the couple’s fertility history. In many cases, pregnancy is achieved within 1–3 IVF cycles.

What is the cost of a complete IVF treatment?

The cost can start at ~3,500 and reach or exceed 5,500, depending on whether egg donation, cryopreservation or special techniques are required.

Does the IVF process hurt?

The process is basically painless. Egg retrieval is performed under mild anaesthesia and takes about 15-30 minutes. The injections of medication may cause minor discomfort, such as bloating or sensitivity in the abdomen.

What are the success rates by age?

In women under 35, success rates are around 50–70%. After 40, the rates gradually decrease, while egg donation significantly increases the chances regardless of age.

When can I take a pregnancy test after embryo transfer?

The measurement of beta-hCG is usually performed 10–12 days after embryo transfer, with a blood test. Home pregnancy tests are not recommended before this time.

Our Doctors

In an era where fertility requires knowledge, care, and substantial guidance, FertUlity is not an impersonal clinic. It is two people who look you in the eye and accompany you step by step on the journey you dream of.

Dr. Chrysostomos (Makis) Papadopoulos Obstetrician – Gynecologist, MD, PhDc, MIC I

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Dr. Chrysostomos Papadopoulos - Specialist in Infertility, Endocrinology & Menopause in Athens

Dr. Maria Oikonomou Obstetrician – Gynecologist

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The First Step Starts Now

You don’t need to have all the answers to begin.
All it takes is one first step, and a team that truly listens.

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FertulityThrough the Words of our Parents

100% genuine, public Google reviews.
Because every fertility journey begins with honesty and trust.

      EXCELLENT  
   Based on 12 reviews 
    
 
 
 
   
 
 
      Posted on Google  
   
   Μαρια 
 26 days ago
 
 
  The word "thank you" to Dr. Makis Papadopoulos is too small to describe the gratitude we feel for this man. I am pregnant after IVF, having succeeded on the first attempt, and we owe this exclusively to our doctor. First Contact & Communication: From the very first contact, he won us over with his kindness, enthusiasm and willingness to dedicate as much time as we needed. Willing to explain everything in every detail, he solved every question we had in depth — not even a professor to students would analyze them with such patience and contagiousness! Scientific Training: He is an excellent scientist, with deep knowledge of the subject, a perfectionist and focused professional who leaves absolutely nothing to chance. He designed the right treatment for us, solving every problem down to the last detail, making us feel that whatever problem arises, it is certain that it will be solved. HUMANITY & SUPPORT: The most important thing, however, is his humanity. Communication with him was Immediate and he always had as much time as you needed on the phone to solve every question. He showed a deep, real interest, embracing us not just as a doctor, but as if he were our brother. We highly recommend him to every couple starting this journey. He deserves blind trust! We thank you from the bottom of our hearts for the greatest miracle of our lives!

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   Alexandra 
 52 days ago
 
 
  I don't often write reviews, but I feel that Mr. Makis truly deserves it. From the very first moment, he made me feel safe and confident. He listened carefully to what was on my mind, answered every question I had, and explained everything in a simple way, always based on scientific data. Many times, he even sent me relevant scientific studies so that I could better understand why he was suggesting a particular approach. But what stood out to me the most was that he didn't stop at the appointment. He followed up, was genuinely interested in my progress, and was available when I needed him. This is something you rarely encounter. Fortunately, he returned to Greece. He is one of the few doctors who, beyond their knowledge, remain above all human beings. He makes you feel like he sees you as a person and not as just another incident.

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   Matina 
 69 days ago
 
 
  A big thank you to Dr. Makis Papadopoulos who supported us from day one, who checked every little detail, who explained to us every move-step, every test, every medication for the reason we were doing it and what we would achieve. With incredible experience, knowledge, a lot of patience (because we had two other failed attempts with another doctor) and trust, within 8 months he adapted the protocols for our case and we achieved the positive result and we hold in our arms a priceless diamond. Above all, a rare person, calm and always available to listen to our concerns and reassure us. I highly recommend him!

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   Eva 
 93 days ago
 
 
  Thanks to Dr Makis Papadopoulos, I am now holding my two beautiful babies in my arms! He is a true expert. Professional with a human centric approach, friendly and empathetic, always available to answer our (many many) questions. I trust Dr Makis blindly and, honestly, I cannot recommend him enough!
  
 
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   Ivy 
 100 days ago
 
 
  My experience with Dr. Makis took me from a clinical stagnation to an incredible breakthrough, highly recommend Dr. Makis! Navigating the exhausting world of IVF, you know how devastating it is to watch your protocol dosages go up while your results go down. After three intense, high-dosage cycles with a previous clinic, I was left feeling incredibly discouraged. Despite escalating medications and growth hormones, my blastocyst yield was dwindling, culminating in a heartbreaking round with zero blastocysts. I knew I needed a doctor who didn't just follow a standard script, but who truly understood the nuances of egg quality and customized protocols. That is when I found Dr. Makis. Dr. Makis completely revolutionized my treatment plan. Instead of just pushing maximum dosages, he took a highly strategic, tailored approach. The result? Quality over pure protocol size. While my previous doctors kept increasing the medication dosages (which yielded fewer or zero blastocysts), Dr. Makis completely changed the strategy. He lowered the heavy stimulation, introduced smart egg-quality support (like melatonin), changed the protocol style entirely, and achieved a 700% increase in blastocysts compared to my best previous rounds. Beyond the incredible results, Dr. Makis brings a level of expertise, precision, and reassuring care that is rare to find. He looks at you as an individual, not a statistic, and knows exactly how to pivot when traditional routes fail. If you are looking for a specialist who can turn a difficult prognosis into an overwhelming success, look no further than Dr. Makis. I am incredibly grateful for his care.
  
 
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   Olga 
 111 days ago
 
 
  Dr. Makis Papadopoulos was excellent, professional, and very reassuring throughout the entire process. Thanks to his expertise and guidance, we were able to identify the issue early and take the appropriate steps from the beginning. He took the time to explain everything clearly, answered all our questions with patience, and made us feel comfortable and confident throughout our journey. We truly appreciated his caring approach, professionalism, and dedication. Highly recommended!
  
 
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   Euaggelia 
 122 days ago
 
 
  Dr. Makis Papadopoulos is an excellent scientist and above all a rare person! He is an approachable and smiling doctor, with excellent medical knowledge, who from the first moment I met him made me feel comfortable and trust him completely, answering every question I had with patience and documenting every answer with scientific studies and articles! The most important thing, however, is that Dr. Makis Papadopoulos is always there on the other end of the line to listen to you and reassure you without a trace of haste, a doctor who truly cares and makes you feel like he is your own person! Makis, thank you very much for everything!!! I am very lucky to have met you!

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   Anastasia 
 129 days ago
 
 
  Dr. Makis Papadopoulos is an excellent scientist with a human-centered interest. Our collaboration was excellent from the very beginning and he made me feel confident and secure by explaining every step of the process in great detail. I highly recommend him!

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   Fay 
 131 days ago
 
 
  Dr Makis Papadopoulos is very professional, caring and attentive. Very thorough in explaining the whole process throughout every step. Thank you! Highly recommended!!
  
 
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   Christina 
 134 days ago
 
 
  I would like to share my experience with Dr. Makis Papadopoulos, an outstanding gynecologist and scientist. We first connected in the summer of 2024, while he was based in Germany, through a mutual acquaintance, following a particularly challenging period for us. Prior to meeting him, we had gone through repeated unsuccessful attempts of stimulation and fertilization with other gynecologists. Unfortunately, those approaches relied largely on standardized protocols, without sufficient personalization to address the specific needs of my case. From the very beginning, Dr. Makis stood out for his human-centered approach and his willingness to dedicate time to truly understand our situation in depth. With strong, up-to-date scientific knowledge, he approaches every case holistically, focusing on individualized treatment and adapting protocols to the patient's unique needs. Throughout our collaboration, which now spans approximately two years (with a few breaks on our side), he has consistently been available, supportive, and clear in his guidance. He inspired confidence and helped us stay positive even during difficult phases of the journey. Beyond his scientific expertise, what truly sets him apart is his genuine care for the person behind each case: his empathy, honesty, and continuous effort to achieve the best possible outcome. My husband and I are deeply grateful for his support and guidance, and we now feel ready and optimistic to move forward to the next final stage. We highly recommend him to anyone seeking a gynecologist with true expertise, professionalism, and compassion. I would like to share my experience with Dr. Makis Papadopoulos, an excellent gynecologist and scientist. We met in the summer of 2024, when he was in Germany, through a mutual acquaintance, after a particularly demanding period for us. Before meeting him, we had gone through repeated failed attempts at stimulation and fertilization with other gynecologists. Unfortunately, the approaches that had been followed were mainly based on standardized protocols, without the necessary individualization to the specifics of my case. From the beginning, Dr. Makis stood out for his human approach and his willingness to spend time to understand our case in depth. With modern knowledge and scientific training, he approaches each issue multidimensionally, emphasizing the individualization of treatment and adapting the protocols to the real needs of the patient. During our collaboration, which now spans about two years (with short breaks on our part), he was always available, supportive and clear in his guidance. He inspired confidence in us and helped us remain optimistic even in difficult phases. In addition to his scientific competence, what sets him apart is his genuine interest in the person behind each case: his empathy, his honesty and his constant effort to achieve the best possible outcome. My husband and I thank him warmly for his support and guidance and we now feel ready and optimistic to move on to the next final stage. We highly recommend him to anyone looking for a gynecologist with real knowledge, professionalism and humanity.

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   Faidra 
 135 days ago
 
 
  Dr. Makis Papadopoulos is an excellent gynecologist and above all an excellent person! I truly thank him for his support and care during the egg freezing process. Although my case was particularly demanding, he stood by me with patience, knowledge, great experience and real interest. Our communication was direct and human, while his availability at the many appointments made me feel safe at every step. The protocols were designed specifically for me, aiming for the best possible result, while also taking into account the cost of the medications. I recommend him with all my heart to every woman who wants to trust someone for something so important and sensitive for her.

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   Iliana 
 137 days ago
 
 
  I highly recommend Dr. Makis, he is an incredible specialist. My journey was far from easy, encountering several challenges that  made the process feel overwhelming at times. What sets him apart is his willingness to go beyond standard procedures. He developed a specialized, custom protocol, tailored to my situation, which ultimately made all the difference. Beyond his technical expertise, his calm and clear communication kept me grounded throughout the process. I am so grateful for his persistence and high level of care!

Why choose FertUlity?

Because every fertility journey deserves the right support. At FertUlity, we provide science-based fertility care with a human approach. We support every path, from fertility assessment and preservation to modern assisted reproduction.

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Knowledge brings confidence. At FertUlity, we share evidence-based information so you can make the right decisions about your fertility.

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