Fertulity IVF
Fertulity IVF

Sperm Quality The Essential First Step Toward Solving Male Infertility

Fertility involves both partners. In 40% of cases, male infertility is the main or sole factor. However, proper diagnosis brings the solution – and that solution begins with one simple step: evaluating sperm quality.

What Is Sperm Quality Testing?

Sperm quality testing is a simple, non-invasive procedure that provides valuable information about a man's fertility. The classic semen analysis, as well as specialized tests such as sperm DNA fragmentation and oxidative stress – all offered at our clinic – give us a complete picture of a man’s reproductive health. Through advanced diagnostic tools, we can thoroughly assess the functionality, viability, and genetic profile of sperm cells.

At FertUlity, we understand that infertility is a condition that causes anxiety and stress for couples. Nevertheless, our clinic offers many treatment options designed to effectively address male infertility. However, the first step is proper and timely diagnosis so that a suitable treatment strategy can be planned, personalized for each patient.

When Is Sperm Quality Analysis Necessary?

Semen testing is an integral part of the basic fertility evaluation for any couple facing conception difficulties. It is especially important:
In cases where pregnancy is delayed for more than 6 to 12 months
When the female partner has a history of infertility or has started related tests
In preparation for assisted reproduction treatments such as IVF
When risk factors exist such as varicocele, inflammation, chemotherapy, or exposure to toxic substances
In cases of previous unsuccessful artificial insemination attempts

What Does Sperm Quality Evaluation Include?

Laboratory testing includes multiple analyses that together provide a complete picture of a man's reproductive potential:

Semen Analysis

Semen analysis is a traditional laboratory test where key characteristics of a man’s sperm are assessed. A sample is collected after 2 to 5 days of abstinence and analyzed within a specific time window to ensure accurate and reliable results. The main characteristics evaluated include:
Total sperm count, which shows the testes’ production capacity
Motility — how quickly and straight the sperm swim, crucial for reaching the egg
Morphology — the percentage of sperm with normal shape, which relates to their ability to penetrate the egg
Additional criteria include:
Presence of white blood cells, which may indicate inflammation or infection in the male reproductive system
pH level, which may reveal abnormalities in the sperm environment
Viscosity or liquefaction time, which affect the sperm’s ability to function properly

Advanced Male Fertility Testing

If the basic semen analysis shows abnormal findings, more specialized tests may be needed. These include:
Sperm DNA fragmentation testing to assess the genetic integrity of sperm
FISH test to detect chromosomal abnormalities
Semen culture to identify infections or inflammation
Macroscopic ejaculation evaluation to assess retrograde ejaculation or rare anomalies
Hormonal testing (FSH, LH, testosterone) to detect endocrine-related causes
This comprehensive approach allows the couple to receive targeted guidance and avoid unnecessary or inappropriate interventions.

How Reliable Is the Test?

The reliability of sperm analysis depends heavily on the sample collection method, delivery time, and the experience of the microbiologist. It is recommended to collect the sample in a special room within the clinic or to deliver it quickly from home following specific instructions.

In many cases, a single semen analysis is not enough to form a complete picture of sperm health. Combining semen analysis with advanced fertility tests and repeating the analysis after 2–3 weeks helps draw more reliable conclusions, as sperm quality can be temporarily affected by illness, infection, stress, diet, or medication.

Frequently Asked Questions About Sperm Quality Analysis

Is the sample collection process painful?

No, the sample is collected via masturbation in a private clinic room or at home using a special non-toxic condom, following the doctors’ instructions. Sperm sample collection is simple, painless, and discreet.

Can stress affect the results?

Yes, high stress levels can impact both sperm motility and count. That’s why repeating the test after 2–3 weeks is recommended.

What should I avoid before sample collection?

It is recommended to abstain from any sexual activity for 2–5 days before the test and avoid intense physical activity.

Are there medications or supplements that improve quality?

Yes, taking antioxidant supplements and avoiding smoking, alcohol, and heat exposure has been positively linked to improvements in sperm quality parameters measured during analysis.

Our Doctors

In an era where fertility requires knowledge, care, and substantial guidance, FertUlity is not an impersonal clinic. It is two people who look you in the eye and accompany you step by step on the journey you dream of.

Dr. Maria Oikonomou Obstetrician – Gynecologist

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Dr. Chrysostomos (Makis) Papadopoulos Obstetrician – Gynecologist, MD, PhDc, MIC I

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Why choose FertUlity?

Because every fertility journey deserves the right support.

At FertUlity, we provide science-based fertility care with a human approach.
We support every path, from fertility assessment and preservation to modern assisted reproduction.

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